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Amitriptyline HCl Manufacturing Thailand, the United Kingdom and USA
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Amitriptyline HCl

  • Product Name : Amitriptyline HCl
  • Grade : IP / BP / USP
  • Therapeutic Category : Anti anxiety
  • CAS No : 549-18-8
  • Other Name : Amitriptyline
  • COA : Available
  • MSDS : Available

Description

Description:

Amitriptyline Hydrochloride is an antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptakeof norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters.

Usage:

 Amitriptyline is used in ankylosing spondylitis for pain relief as a preventive for patients with frequent/chronic migraines. It is also used as a preventive for patients with recurring biliary dyskinesia (sphincter of Oddi dysfunction) Amitriptyline is also used in the treatment of nocturnal enuresis in children.

Specification:

 

Description

white or practically white, odorless or practically odorless, crystalline powder or small crystals

Solubility

Freely soluble in water, in alcohol and in Chloroform, and in methanol, insoluble in ether.

Identification:

Test A

Test B

Test C

 

BY IR

BY UV

Test for Chloride

Melting Range

Between 195.0°C to 199.0°C

Related Substances By TLC

Any secondary spot : NMT 0.5%

Sum of all secondary spots : NMT 1.0%

Heavy metals

Not more than 0.001%

Loss On Drying

Not more than 0.5%

 

  Packaging details:

Packaging details:

25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.

Storage:

Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat

Shelf Life:

5 years if sealed and store away from direct sun light.

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